{"id":1760,"date":"2012-08-28T18:18:26","date_gmt":"2012-08-29T01:18:26","guid":{"rendered":"http:\/\/wordpress.reed.edu\/chem201202\/2012\/08\/william-perkin-meet-silas-cook.html"},"modified":"2014-03-18T10:13:01","modified_gmt":"2014-03-18T17:13:01","slug":"william-perkin-meet-silas-cook","status":"publish","type":"post","link":"https:\/\/blogs.reed.edu\/chem201202\/2012\/08\/william-perkin-meet-silas-cook\/","title":{"rendered":"William Perkin? Meet Silas Cook!"},"content":{"rendered":"<p>\n\tOrganic chemistry has a long history. This week we took a look at<strong> William Perkin<\/strong>, whose &quot;unsuccessful&quot; preparation of quinine spawned an entire industry, and <strong>Silas Cook, Reed &#039;99<\/strong>, who recently supervised the first <a href=\"http:\/\/pubs.acs.org\/doi\/abs\/10.1021\/ja3061479\" target=\"_blank\"><strong>short &quot;total&quot; synthesis of artemisinin<\/strong><\/a>.<\/p>\n<p>\n\tA closer look at the following web pages reveals that I reported some dates incorrectly in class: Queen Victoria wore a mauve-colored dress, but not until after the Royal Exhibition of 1851 was just a memory.<\/p>\n<p>\n\tA nice book on the subject of Perkin, mauve, etc., is<a href=\"http:\/\/www.amazon.com\/Mauve-Invented-Color-Changed-World\/dp\/product-description\/0393323137\" target=\"_blank\"><strong> Mauve: How One Man Invented a Color that Changed the World<\/strong><\/a>. You can also learn quite a bit at these links:<\/p>\n<ul>\n<li>\n\t\t<a href=\"http:\/\/en.wikipedia.org\/wiki\/William_Henry_Perkin\" target=\"_blank\"><strong>William Perkin<\/strong><\/a>, 1838-1907. The teenager who &quot;dyed&quot; Queen Victoria purple<\/li>\n<li>\n\t\t<a href=\"http:\/\/en.wikipedia.org\/wiki\/August_Wilhelm_von_Hofmann\" target=\"_blank\"><strong>August Wilhelm von Hofmann<\/strong><\/a>, 1818-1892. The professor who took on a precocious 15-year-old assistant. Wikipedia also describes him as the first lecturer to make use of molecular models<\/li>\n<li>\n\t\t<a href=\"http:\/\/en.wikipedia.org\/wiki\/Quinine\" target=\"_blank\"><strong>Quinine<\/strong><\/a>, an early treatment for malaria obtained from the cinchona tree<\/li>\n<li>\n\t\t<a href=\"http:\/\/en.wikipedia.org\/wiki\/Artemisinin\" target=\"_blank\"><strong>Artemisinin<\/strong><\/a>, a &quot;new&quot; treatment for malaria obtained from sweet wormwood<\/li>\n<li>\n\t\t<a href=\"http:\/\/en.wikipedia.org\/wiki\/Mauveine\" target=\"_blank\"><strong>Mauveine<\/strong><\/a>, the dye that transformed commoners into royalty<\/li>\n<li>\n\t\t<a href=\"http:\/\/www.indiana.edu\/~cooklab\/\" target=\"_blank\"><strong>Silas Cook<\/strong><\/a> (Reed &#039;99), Chemistry Department, U. Indiana. His Reed thesis title was: &quot;The synthesis of 3,5-bis(carboranyloxy)benzaldehyde : the precursor to a novel boronated porphyrin for use in boron neutron-capture therapy&quot;<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p> Organic chemistry has a long history. This week we took a look at William Perkin, whose &quot;unsuccessful&quot; preparation of quinine spawned an entire industry, and Silas Cook, Reed &#039;99, who recently supervised the first short &quot;total&quot; synthesis of artemisinin&#8230;.<\/p>\n","protected":false},"author":55,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-1760","post","type-post","status-publish","format-standard","hentry","category-post-lecture"],"_links":{"self":[{"href":"https:\/\/blogs.reed.edu\/chem201202\/wp-json\/wp\/v2\/posts\/1760","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.reed.edu\/chem201202\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.reed.edu\/chem201202\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.reed.edu\/chem201202\/wp-json\/wp\/v2\/users\/55"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.reed.edu\/chem201202\/wp-json\/wp\/v2\/comments?post=1760"}],"version-history":[{"count":2,"href":"https:\/\/blogs.reed.edu\/chem201202\/wp-json\/wp\/v2\/posts\/1760\/revisions"}],"predecessor-version":[{"id":5109,"href":"https:\/\/blogs.reed.edu\/chem201202\/wp-json\/wp\/v2\/posts\/1760\/revisions\/5109"}],"wp:attachment":[{"href":"https:\/\/blogs.reed.edu\/chem201202\/wp-json\/wp\/v2\/media?parent=1760"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.reed.edu\/chem201202\/wp-json\/wp\/v2\/categories?post=1760"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.reed.edu\/chem201202\/wp-json\/wp\/v2\/tags?post=1760"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}