Oliver Laeyendecker ’90 receives PhD in Epidemiology

Oliver wrote to us in mid-May that he was about to receive his PhD in Epidemiology later that month from the Johns Hopkins School of Public Health. His PhD will share shelf space with MS and MBA degrees that Oliver had previously collected.

Laeyendecker_Oliver_2013Oliver wrote, “My thesis was on the development of accurate methods to estimate HIV incidence from a cross-sectional survey. It turned out to be a very productive project with lots of publications (PubMed). The Johns Hopkins Center for AIDS Research asked me to do a presentation on this topic, which is available on YouTube. This presentation had a good deal of overlap with my thesis defense.

Thank you again for inspiring the application of rigors scientific methods so many years ago. I still treasure my memories from my days at Reed as a chemistry student.”

When Oliver isn’t in front of the office computer or the video camera, he’s busy being a father for two active children, 12 and 16. As he put it, “I am happy to still have any hair.”

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Alumni News from Reed Magazine, September ’12

Summer is just around the corner and now is the time to start constructing that summer reading list. So why not start with some back issues of the Reed Magazine?

The September ’12 issue featured a profile of new president, John Kroger. While John is not a chemist, another Reedie is a president. Chantal Sudbrack ’97, president of the national alumni board, can be found on p. 11 (Meet Your Alumni Board) alongside other board members. Chantal also writes periodically in the Empire of the Griffin blog.

Prof. Kevan Shokat '87

Prof. Kevan Shokat ’86

A much longer profile (“The Molecular Assassin”, p. 20) follows Prof. Kevan Shokat ’86 through his day at UC San Francisco’ Mission Bay biosciences campus. Kevan, as the article states (and his colleagues worldwide will affirm) “is a rock star: a member of the National Academy of Sciences and the American Academy of Arts and Sciences, Eli Lilly Award winner, Sloane Fellow, and Searle Scholar”. But what comes across in the article is not so much “rock star”, as “driven scientist”. This article bears multiple readings. [A correction to “Thirty years after Chemistry 101 and well into his own career”. That line should have read 110, not 101. The intro chem sequence was changed long after Kevan’s graduation.]

Continue reading

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Prof. Emeritus Pat McDougal

After serving 22 years as a Reed chemist, and the past two years as Acting Dean of the Faculty, Prof. Pat McDougal has decided to retire from Reed effective June 1, 2013. A retirement celebration will be held during Reedfayre 2013 on Friday, June 14, 2:15-4:15 PM, in Vollum Lounge.

mcdougal2013Practically since his arrival at Reed in fall 1990, Pat has enjoyed iconic status among chemistry students as a maker of molecules, and among faculty and administrators as a source of wisdom on all things Reed. Pat’s enthusiasm for chemistry and his devotion to Reed students can be seen in the large number of academic offspring who have found jobs as synthetic chemists, either as faculty or in the chemical industry.

While Pat is well-known across campus for his teaching contributions in Chem 202, 343 (re-dubbed years ago by worshipful Reedies as “Advanced Pat”), 470, and Senior Symposium, few members of the community were aware of his pre-Reed history as an organic chemistry graduate student/TA in the late 70’s at University of Wisconsin-Madison (PhD ’82), or his stint as a chemistry professor at Georgia Tech (1983-90). Some of these unfamiliar stories and photographs (below: Pat on the streets of Madison ca. 1979-80) were shared by UW classmate and Reed colleague, Prof. Alan Shusterman (PhD ’81) at the annual end-of-year faculty lunch on May 17.

Pat McDougal Madison WI Spring 1980

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Emily Dykhuizen ’01 et al. move to Purdue

Emily just updated her ‘Reed profile’ with this email to Arthur, “It’s been a crazy year. I’m finishing up my postdoc in a couple months and my husband and I are both starting faculty positions at Purdue University in the Department of Medicinal Chemistry and Molecular Pharmacology. We only applied to a handful of schools thinking that it would take a couple years to get two positions in the same place. Plus, I had a baby last summer and applying for dozens of jobs turned out to be too much work. I still can’t believe it worked out this year, but I am very happy and ready to start the next stage of my career. Also, I have a paper coming out in Nature next week, so keep an eye out for that!”

FYI – Emily is wrapping up a postdoc in the ‘CrabLab‘ (Jerry Crabtree laboratory) at Stanford.

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Cole Perkinson ’13 Wins Watson Fellowship

Cole Perkinson, who will graduate Monday with an interdisciplinary degree in chemistry-physics, happens to a wonderfully talented musician with eclectic tastes. Many classmates still remember when he ‘brought the house down’ on the last day of intro chem with his rendition of Tom Lehrer’s ‘The Elements’ and he has performed for several years in the Reed Collegium. But Cole is much more than a singer; he also plays several instruments ranging from classical piano to African marimba.

Talent like this doesn’t go unnoticed. Graduate school plans have been put on hold so that Cole can take advantage of a $25,000 Watson Foundation fellowship to study music in Africa next year. You can read more about Cole’s musical background and family, his travel plans, and watch a short clip of him performing with the marimba at “Cole Perkinson, Reed student, wins $25,000 Watson Fellowship to study music in Africa” (D. Stabler, Oregonian, May 11).

Congratulations, Cole!

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The PhD Phactory

Where do science and engineering (S&E) Ph.D.’s come from? That’s a question that the National Science Foundation has been asking for a long time and the answers may surprise you. Last month, the NSF published its most recent answer online in a free-to-the-public report, Baccalaureate Origins of U.S.-trained S&E Doctorate Recipients

The report summarizes the data in several interesting ways, but the most interesting table might be Table 4, Top 50 Institutions [ordered by] institutional-yield ratio. The data shown here answer the question, Starting with 100 bachelors degree recipients, how many go on to earn an S&E PhD?

  1. Caltech 34.9%
  2. Harvey Mudd 24.4%
  3. MIT 16.0%
  4. Reed College 14.2%

Yup, that’s right. Reed, which has no engineering program and which asks every incoming student to spend a year contemplating Homeric epics, is the #4 PhD factory in the entire country.

Which leads to another question: just how many Reed students even earn degrees in science? That answer (and many other interesting tidbits about Reed) can be found here in Facts About Reed. 413 Reedies (26.2%) have received science degrees in the past 5 years out of 1579 total. Combining* the two figures suggests that about 54% of our science grads earn PhDs. Take that, Caltech! 😉

*disclaimer: I obtained 54% by comparing NSF and Reed data from different time periods, but the Reed percentages have been very consistent for decades

 

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Analytical chemistry and ‘The Con Man’

One wouldn’t think that a story about scientific fraud would arouse a lot of passion among the reading public unless it had something to do with climate change or water fluoridation, but a NY Times story from this past weekend’s magazine (The Mind of a Con Man, April 28, 2013) generated over 360 comments in just a few hours. Some had a lot to say, but Dr. Allison Stelling ’04, had offered this short assessment of fraud, the virtues of analytical chemistry, and something that she remembered her A-chem prof, Ron McClard, saying:

“My undergraduate thesis adviser at Reed College, Prof. McClard, once said during his always amusing analytical chemistry lecture: “When you become wedded to your hypothesis rather than to your data, that’s a little bit scary.” Sometimes I think social and life sciences would benefit if a solid analytical chemistry course were a requirement for the majors.”

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‘Thank You’ to Our Supporters

Reed’s Centennial Campaign was launched in 2005 with lofty financial goals and even loftier ideas about how to spend the money. Two years later, the financial industry tanked, but the campaign plugged along. Eventually, an enthusiastic band of Reed supporters donated over $200,000,000 in new gifts to the college.

You can read more about the campaign here. You can also watch a ‘Thank You’ video that includes a segment showing Danielle Draper ’13 and her thesis advisor, Prof. Julie Fry (link is near the bottom of the Reed Magazine page; update 4/9 more information about the campaign and an easier-to-find link to the video is available here)Centennial Campaign 'Thank You'

But most of all, the Reed chemists would like to express our gratitude to all those who participated in the campaign. Everything we accomplish is made possible with your fabulous support. Thank you!

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Can Malaria Be Wiped Out?

The jury is still out on this question, but a new drug target has raised the hopes of malaria researchers that the disease can be treated more effectively in the future. The new compound, ELQ-300, was developed by a team of scientists at Portland’s Veteran Affairs Medical Center led by Michael Riscoe that included Reed visiting professor Aaron Nilsen and Kip Guy, ’89.
ELQ-300

The first paper describing ELQ-300 has just appeared in Science Translational Medicine (DOI: 10.1126/scitranslmed.3005029) with Aaron as the lead author, and popular accounts have appeared this week in Chemistry & Engineering News (2013 March 25, p. 35) and on the front page of the Oregonian (2013 March 21).

But stay tuned. Aaron tells me that Galen Miley ’13, his thesis student, has prepared a compound that is even more effective than ELQ-300.

6/11/2013 update: Randie Dalziel just told me about this recent article: Experimental malaria drug may be a hot prospect | Body & Brain | Science News, April 20, 2013, vol. 183 #8.

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Aaron Nilsen, Microbe Hunter

Aaron Nilsen, 2012-13
One year ago the Chemistry department found itself in a bind. Our visiting professor of organic chemistry, Luc Boisvert, was scheduled to begin teaching at the University of Puget Sound in the fall, and our regular professor of organic chemistry, Pat McDougal, had just agreed to extend his stay in the Dean of the Faculty office. With a record number of junior chemistry majors (27) and a bumper crop of intro organic students (81) advancing towards our labs, panic seemed like the only reasonable option.

Fortunately, the situation was quickly resolved when Dr. Aaron Nilsen, a research scientist at the Portland VA Research Foundation agreed to take a one-year leave from his research position in order to teach at Reed. Aaron, who grew up in the coastal redwood community of Ben Lomond, California, first learned about Reed as a UC Santa Cruz graduate student in the lab of Rebecca Braslau ’81 and he had been interested in trying his hand at chemistry teaching for some time. Indeed, once on campus, he quickly saw ways in which his research interests could be put to use in Chem 202 and 343, and he soon attracted a large cadre of hardworking research students.

Aaron describes his approach to research this way: “Organic synthesis applied to chemical biology and medicinal chemistry. Students in my research lab work toward translation of structure activity relationships, derived from previously synthesized compounds, literature and high-throughput screens, to the synthesis of biologically active molecules that provide insight into the mechanisms of action of these molecules on their respective parasitic or viral systems.”

But you can just cut to the chase and say: Aaron Nilsen, Microbe Hunter.

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