I took a pathway that I know pretty well, NMDA-based long term potentiation (the process by which neurons become more sensitive to neurotransmitters in response to glutamatergic activity). I made some positives for both the first part of the pathway, the channel proteins that bind to and Ca2+ associated proteins, and the last part of the pathway, which involves nuclear proteins involved with transcribing growth factors and new channel proteins.<\/p>\n
A protein centrally implicated in LTP, CaMKII, was used as the reference ranked 21 out of ~15,000. It’s good, but it could be improved. It might be better if we allowed for more precision.<\/p>\n
Upcoming tasks will include further verifications, but will probably be postponed, since both of us are taking the biology junior qualifying exam, which is a cumulative exam that we need to pass to graduate.<\/p>\n","protected":false},"excerpt":{"rendered":"
I took a pathway that I know pretty well, NMDA-based long term potentiation (the process by which neurons become more sensitive to neurotransmitters in response to glutamatergic activity). I made some positives for both the first part of the pathway, the channel proteins that bind to and Ca2+ associated proteins, and the last part of … Continue reading “Week 20”<\/span><\/a><\/p>\n","protected":false},"author":1584,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7,8,1],"tags":[],"class_list":["post-208","post","type-post","status-publish","format-standard","hentry","category-creu","category-schizophrenia","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/blogs.reed.edu\/compbio\/wp-json\/wp\/v2\/posts\/208","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.reed.edu\/compbio\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.reed.edu\/compbio\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.reed.edu\/compbio\/wp-json\/wp\/v2\/users\/1584"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.reed.edu\/compbio\/wp-json\/wp\/v2\/comments?post=208"}],"version-history":[{"count":1,"href":"https:\/\/blogs.reed.edu\/compbio\/wp-json\/wp\/v2\/posts\/208\/revisions"}],"predecessor-version":[{"id":209,"href":"https:\/\/blogs.reed.edu\/compbio\/wp-json\/wp\/v2\/posts\/208\/revisions\/209"}],"wp:attachment":[{"href":"https:\/\/blogs.reed.edu\/compbio\/wp-json\/wp\/v2\/media?parent=208"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.reed.edu\/compbio\/wp-json\/wp\/v2\/categories?post=208"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.reed.edu\/compbio\/wp-json\/wp\/v2\/tags?post=208"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}