{"id":472,"date":"2019-06-06T11:30:46","date_gmt":"2019-06-06T18:30:46","guid":{"rendered":"http:\/\/blogs.reed.edu\/compbio\/?p=472"},"modified":"2019-06-14T15:52:46","modified_gmt":"2019-06-14T22:52:46","slug":"summer-research-2019-here-we-go","status":"publish","type":"post","link":"https:\/\/blogs.reed.edu\/compbio\/2019\/06\/06\/summer-research-2019-here-we-go\/","title":{"rendered":"Summer Research 2019 &#8211; here we go!"},"content":{"rendered":"\n<div class=\"wp-block-image\"><figure class=\"aligncenter is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/webapps.macalester.edu\/calendar\/event-imgs\/full\/stand_back_i_m_going_to_try_sc.jpg\" alt=\"\" width=\"335\" height=\"236\" \/><\/figure><\/div>\n\n\n\n<p>Reed has finished for the year, but that doesn&#8217;t mean that students are done. Last week kicked off a slew of undergraduate researchers doing all kinds of research.  In no particular order, here&#8217;s a taste of what people will be working on in the compbio lab.  Stay tuned for occaisonal group updates.<\/p>\n\n\n\n<p>Math-CS major <strong>Jiarong (Lee) Li &#8217;21<\/strong> and biology major<strong> Tunc Kose &#8217;22<\/strong> are going to develop algorithms to analyze a cell&#8217;s response to external signals (called <em>signaling pathways<\/em>). They will be working to extend ideas based on the original <a href=\"https:\/\/www.nature.com\/articles\/npjsba20162\">PathLinker paper <\/a>and Ibrahim Youssef&#8217;s <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/609149v1\">Localized-PathLinker<\/a> paper. <\/p>\n\n\n\n<p>Recent graduate <strong>Amy Rose Lazarte &#8217;19<\/strong> (alt. bio major with a CS emphasis) will continue to develop a resource and modeling framework for understanding the effect of thermal variation on freshwater phytoplankton.  Co-advised by ecologist <a href=\"https:\/\/www.reed.edu\/biology\/fey\/\">Sam Fey<\/a>, she has developed a computational pipeline to analyze <a href=\"https:\/\/lter.limnology.wisc.edu\/\">longitudinal lake temperature data<\/a> using simulations of phytoplankton swimming strategies.<\/p>\n\n\n\n<p>Biology major <strong>Tayla Isensee &#8217;20<\/strong> is working on identifying targets of retinoic acid signaling in zebrafish eye development.  She has a hand in the wetlab work with developmental biologist <a href=\"https:\/\/www.reed.edu\/biology\/cerveny\/\">Kara Cerveny<\/a>, and she will be building a zebrafish protein-protein interaction network to find potential regulators to test.  First, though, she&#8217;s going to hunt for retinoic acid response elements (RAREs) in the zebrafish genome to identify direct targets of retinoic acid.<\/p>\n\n\n\n<p>Another recent graduate, neuroscience major <strong>Alex King &#8217;19,<\/strong> will be wrapping up his thesis work to build a network that integrates gene, transcript, and protein relationships in order to identify dysregulated pathways in polygenic diseases based on genome-wide association study (GWAS) data. <\/p>\n\n\n\n<p>Biology major <strong>Karl Young &#8217;20<\/strong> will be reading up on computational modeling in neuroscience, and figuring out the intersection of my world (algorithms for biological networks) and neurobiologist <a href=\"http:\/\/www.zorniklab.org\/\">Erik Zornik&#8217;s<\/a> world (neural circuits and how they affect behavior). <\/p>\n\n\n\n<p>Last but not least, CS graduate <strong>Ananthan Nambiar &#8217;19<\/strong> will be getting his thesis ready to present as a poster at <a href=\"https:\/\/www.iscb.org\/ismbeccb2019\">ISMB\/ECCB<\/a> in Basel later this summer. He modeled proteins as language with the help of his main advisor, natural language processing (NLP) expert <a href=\"http:\/\/markandrewhopkins.com\/\">Mark Hopkins<\/a> in CS.  <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Reed has finished for the year, but that doesn&#8217;t mean that students are done. Last week kicked off a slew of undergraduate researchers doing all kinds of research. In no particular order, here&#8217;s a taste of what people will be working on in the compbio lab. Stay tuned for occaisonal group updates. Math-CS major Jiarong &hellip; <a href=\"https:\/\/blogs.reed.edu\/compbio\/2019\/06\/06\/summer-research-2019-here-we-go\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Summer Research 2019 &#8211; here we go!&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1582,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,15,1],"tags":[],"class_list":["post-472","post","type-post","status-publish","format-standard","hentry","category-overviewreview","category-summer-research-2019","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/blogs.reed.edu\/compbio\/wp-json\/wp\/v2\/posts\/472","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.reed.edu\/compbio\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.reed.edu\/compbio\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.reed.edu\/compbio\/wp-json\/wp\/v2\/users\/1582"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.reed.edu\/compbio\/wp-json\/wp\/v2\/comments?post=472"}],"version-history":[{"count":5,"href":"https:\/\/blogs.reed.edu\/compbio\/wp-json\/wp\/v2\/posts\/472\/revisions"}],"predecessor-version":[{"id":479,"href":"https:\/\/blogs.reed.edu\/compbio\/wp-json\/wp\/v2\/posts\/472\/revisions\/479"}],"wp:attachment":[{"href":"https:\/\/blogs.reed.edu\/compbio\/wp-json\/wp\/v2\/media?parent=472"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.reed.edu\/compbio\/wp-json\/wp\/v2\/categories?post=472"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.reed.edu\/compbio\/wp-json\/wp\/v2\/tags?post=472"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}