Here’s the set up: I draw three chemical structures on the board, all of them unfamiliar. Then I ask you some questions: Which one has the strongest odor? Which one raises your body temperature the most? Which one is most effective at strengthening long-term memory? Which one is most effective at curing a case of acne? Which one is most effective at reducing arthritis pain?<\/p>\n
All of these questions ask you to make a predictive leap, starting from a chemical structure and ending at a biological phenomenon, what we call ‘bioactivity<\/strong>‘. As you might expect, this ability to make structure-to-bioactivity predictions is critical in the development of new medicines. However, it could also play a vital role in protecting people from hazardous chemicals. To learn more about predicting the bioactivity of toxic chemicals, check out “Crowdsourcing Toxicity Prediction”<\/strong><\/a> (C&E News, 1 July 2013, p. 18). This could be a good thesis topic…<\/p>\n","protected":false},"excerpt":{"rendered":" Here’s the set up: I draw three chemical structures on the board, all of them unfamiliar. Then I ask you some questions: Which one has the strongest odor? Which one raises your body temperature the most? Which one is most … finish reading Predicting bioactivity of toxic chemicals<\/a><\/p>\n","protected":false},"author":55,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1838","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/blogs.reed.edu\/shusterman_lab\/wp-json\/wp\/v2\/posts\/1838","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.reed.edu\/shusterman_lab\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.reed.edu\/shusterman_lab\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.reed.edu\/shusterman_lab\/wp-json\/wp\/v2\/users\/55"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.reed.edu\/shusterman_lab\/wp-json\/wp\/v2\/comments?post=1838"}],"version-history":[{"count":2,"href":"https:\/\/blogs.reed.edu\/shusterman_lab\/wp-json\/wp\/v2\/posts\/1838\/revisions"}],"predecessor-version":[{"id":1844,"href":"https:\/\/blogs.reed.edu\/shusterman_lab\/wp-json\/wp\/v2\/posts\/1838\/revisions\/1844"}],"wp:attachment":[{"href":"https:\/\/blogs.reed.edu\/shusterman_lab\/wp-json\/wp\/v2\/media?parent=1838"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.reed.edu\/shusterman_lab\/wp-json\/wp\/v2\/categories?post=1838"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.reed.edu\/shusterman_lab\/wp-json\/wp\/v2\/tags?post=1838"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}