Week 16

We have two goals to accomplish for our meeting next week:

  1. Run our iterative method for 100,000 iterations, or until the scores change by 0.001 or less. See how this affects the ranking compared to 150 iterations. Will it just affect the scores but not the relative rankings?
  2. See if the candidates are conserved in drosophila melanogaster. The second part of this project is to experimentally validate the candidates, which we cannot do if they aren’t conserved in drosophila. As a quick sanity check, we’re going to BLAST CTNNB1 (the well-studied Catenin Beta 1 gene that codes for a protein involved in the formation of adherens junctions) in humans against drosophila which should be ARM.

The results will be posted in a couple of days.