The use of animal models as surrogates for humans in scientific experiments goes back centuries. If animals and humans aren’t that different, the thinking goes, we can learn about human biology by studying the biology of our mammalian relatives. According to “Of Mice and Mindfulness” (Reynolds, NY Times – Well, 18 May 2017), the animal model approach might even be used to learn how human brains respond to various mental states, including meditation.
Previous research on humans had revealed a positive correlation between meditation and the amount of white brain matter in a region of the human brain called the anterior cingulate cortex, a part of the brain involved in regulating emotions. Because humans lead such complicated lives, though, researchers could not say whether meditation caused this change in brain matter.
Enter the mouse.